Chloroform → (1-Thiocarbamoylpiperidin-4-yl)acetic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][CH:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1)=[O:14].[CH2:35]1[CH2:36][CH2:37][NH:38][CH2:39][CH2:40]1.[CH:41]([Cl:42])([Cl:43])[Cl:44].[cH:15]1[c:16]2[c:28]([cH:29][cH:30][cH:31]1)-[c:23]1[c:22]([cH:27][cH:26][cH:25][cH:24]1)[CH:17]2[CH2:18][O:19][C:20](=[O:21])[N:32]=[C:33]=[S:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][CH:8]1[CH2:9][CH2:10][N:11]([C:33]([NH2:32])=[S:34])[CH2:12][CH2:13]1)=[O:14]Participants
5
Sources & evidence
- ORD record
- ord-a9ef1c7464fb43b280d7608248aac798
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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