Sodium ion → 6-[(2RS,4SR)-2-(4-chlorophenyl)-2-bromomethyl-1,3-dioxolan-4-ylmethyloxy]-2-(4-phenylbenzyl)-1,2,3,4-tetrahydroisoquinoline

HRID 2335850Notes

Reaction equation

HRID 2335850 reaction equation
[CH3:27][S:28]([O:29][CH2:32][CH:33]1[O:34][C:35]([CH2:38][Br:39])([c:40]2[cH:41][cH:42][c:43]([Cl:46])[cH:44][cH:45]2)[O:36][CH2:37]1)(=[O:30])=[O:31].[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[H-:1].[Na+:2].[OH:3][c:4]1[cH:5][c:6]2[c:11]([cH:12][cH:13]1)[CH2:10][N:9]([CH2:14][c:15]1[cH:16][cH:17][c:18](-[c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[cH:19][cH:20]1)[CH2:8][CH2:7]2>>[O:3]([c:4]1[cH:5][c:6]2[c:11]([cH:12][cH:13]1)[CH2:10][N:9]([CH2:14][c:15]1[cH:16][cH:17][c:18](-[c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[cH:19][cH:20]1)[CH2:8][CH2:7]2)[CH2:32][CH:33]1[O:34][C:35]([CH2:38][Br:39])([c:40]2[cH:41][cH:42][c:43]([Cl:46])[cH:44][cH:45]2)[O:36][CH2:37]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 133618036-Hydroxy-2-(4-phenylbenzyl)-1,2,3,4-tetrahydroisoquinolineHCID 155764512-Bromomethyl-2-(4-chlorophenyl)-1,3-dioxolan-4-ylmethyl methanesulfonate

Product 1

HCID 201558156-[(2RS,4SR)-2-(4-chlorophenyl)-2-bromomethyl-1,3-dioxolan-4-ylmethyloxy]-2-(4-phenylbenzyl)-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-4dd338074e714a7a96a8233132295962
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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