Ammonia → N-(2,6-difluorophenyl)-2-methoxy-5-[3-[2-[2-methoxy-4-[4-(2-methylsulfonylethyl)-3-propan-2-ylpiperazin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Reaction equation
[CH3:36][CH:37]([CH3:38])[CH:39]1[CH2:40][N:41]([c:51]2[cH:52][c:53]([O:58][CH3:59])[c:54]([NH2:55])[cH:56][cH:57]2)[CH2:42][CH2:43][N:44]1[CH2:45][CH2:46][S:47](=[O:48])(=[O:49])[CH3:50].[CH3:68][OH:69].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH3:35])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1.[ClH:60].[F:62][CH2:63][C:64]([F:65])([F:66])[OH:67].[NH3:61]>>[c:2]1([NH:55][c:54]2[c:53]([O:58][CH3:59])[cH:52][c:51]([N:41]3[CH2:40][CH:39]([CH:37]([CH3:36])[CH3:38])[N:44]([CH2:45][CH2:46][S:47](=[O:48])(=[O:49])[CH3:50])[CH2:43][CH2:42]3)[cH:57][cH:56]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][cH:19][c:20]([O:34][CH3:35])[c:21]([C:22](=[O:23])[NH:24][c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])[cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e010a6911a054ccc810276de231a78a8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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