Potassium Cation → tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-[4-(2-oxo-2-phenyl-ethoxy)-phenyl]-piperidine-1-carboxylate

HRID 2335976Notes

Reaction equation

HRID 2335976 reaction equation
[Br:33][CH2:34][C:35](=[O:36])[c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[C:43](=[O:44])([O-:45])[O-:46].[K+:47].[K+:48].[OH:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([O:21][CH2:22][c:23]3[cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]4[cH:31][cH:32]3)[CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([O:21][CH2:22][c:23]3[cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]4[cH:31][cH:32]3)[CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1)[CH2:34][C:35](=[O:36])[c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 6259Phenacyl bromideHCID 19660Carbonate IonHCID 86604423tert-butyl (3RS,4RS)-4-(4-hydroxy-phenyl)-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate

Product 1

HCID 54052928tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-[4-(2-oxo-2-phenyl-ethoxy)-phenyl]-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-0cc9225443124ae3a408bcfe25e72ccf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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