Hydrochloric Acid → Akt1 and Akt2-IN-1

HRID 2335995Notes

Reaction equation

[CH3:1][O:2][c:3]1[c:4]2[cH:5][c:6](-[c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[c:7](-[c:13]3[cH:14][cH:15][c:16]([CH2:19][N:20]4[CH2:21][CH2:22][CH:23]([c:26]5[n:27][nH:28][c:29](-[c:31]6[n:32][cH:33][cH:34][cH:35][cH:36]6)[n:30]5)[CH2:24][CH2:25]4)[cH:17][cH:18]3)[n:8][c:9]2[cH:10][cH:11][n:12]1.[ClH:43].[Na+:54].[O-:50][C:51]([OH:52])=[O:53].[OH2:55].[n:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1>>[O:2]=[c:3]1[c:4]2[cH:5][c:6](-[c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[c:7](-[c:13]3[cH:14][cH:15][c:16]([CH2:19][N:20]4[CH2:21][CH2:22][CH:23]([c:26]5[n:27][nH:28][c:29](-[c:31]6[n:32][cH:33][cH:34][cH:35][cH:36]6)[n:30]5)[CH2:24][CH2:25]4)[cH:17][cH:18]3)[n:8][c:9]2[cH:10][cH:11][nH:12]1

Participants

Reactant 6

HCID 313Hydrochloric Acid

HCID 769Bicarbonate Ion

HCID 923Sodium ion

HCID 962Water

HCID 1049Pyridine

HCID 1784940915-methoxy-3-phenyl-2-(4-{[4-(5-pyridin-2-yl-1H-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-1,6-naphthyridine

Product 1

HCID 178518688Akt1 and Akt2-IN-1

Sources & evidence

ORD record: ord-44c056e1f9cc4ca38d666e75cf0609e1
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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