Acetonitrile → 3-(3-Cyano-6-chloro-5-fluoro-pyridin-2-ylamino)-N-methoxy-4-methyl-benzamide

HRID 2336188Notes

Reaction equation

HRID 2336188 reaction equation
[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:32][C:33]#[N:34].[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([F:11])[c:8]([Cl:10])[n:9]1.[NH2:12][c:13]1[cH:14][c:15]([C:16](=[O:17])[NH:18][O:19][CH3:20])[cH:21][cH:22][c:23]1[CH3:24]>>[c:2]1([NH:12][c:13]2[cH:14][c:15]([C:16](=[O:17])[NH:18][O:19][CH3:20])[cH:21][cH:22][c:23]2[CH3:24])[c:3]([C:4]#[N:5])[cH:6][c:7]([F:11])[c:8]([Cl:10])[n:9]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 27338492,6-Dichloro-5-fluoro-3-pyridinecarbonitrileHCID 207670003-Amino-N-methoxy-4-methylbenzamide

Product 1

HCID 865887993-(3-Cyano-6-chloro-5-fluoro-pyridin-2-ylamino)-N-methoxy-4-methyl-benzamide

Sources & evidence

ORD record
ord-6b0292ed2f5248da80edb033d6bf2a4e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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