Water → N-methyl-1-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyrazole-3-carboxamide

HRID 2336214Notes

Reaction equation

HRID 2336214 reaction equation
[CH3:1][c:2]1[cH:3][c:4]([C:24]([F:25])([F:26])[F:27])[n:5][n:6]1[CH2:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH:13]([n:16]2[n:17][c:18]([C:21](=[O:22])[OH:23])[cH:19][cH:20]2)[CH2:14][CH2:15]1.[CH3:28][N:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1.[CH3:35][NH:36][CH:37]1[CH2:38][CH2:39][CH2:40][c:41]2[cH:42][cH:43][cH:44][cH:45][c:46]21.[Cl:47][CH2:48][Cl:49].[OH2:50]>>[CH3:1][c:2]1[cH:3][c:4]([C:24]([F:25])([F:26])[F:27])[n:5][n:6]1[CH2:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH:13]([n:16]2[n:17][c:18]([C:21](=[O:23])[N:36]([CH3:35])[CH:37]3[CH2:38][CH2:39][CH2:40][c:41]4[cH:42][cH:43][cH:44][cH:45][c:46]43)[cH:19][cH:20]2)[CH2:14][CH2:15]1

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 79724-MethylmorpholineHCID 46475N-methyl-1,2,3,4-tetrahydronaphthalen-1-amineHCID 674614591-[1-[[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-4-piperidinyl]-1H-pyrazole-3-carboxylic acid

Product 1

HCID 69178196N-methyl-1-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyrazole-3-carboxamide

Sources & evidence

ORD record
ord-e84dcadb81054ea2ab9bac18e1d757ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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