Sodium ion → 1'-Benzyl-2-(1-benzylindazol-6-yl)-5'-methylspiro[cyclopropane-1,3'-indole]-2'-one

HRID 2336467Notes

Reaction equation

HRID 2336467 reaction equation
[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[N:10]1[C:11](=[O:20])[CH2:12][c:13]2[cH:14][c:15]([CH3:19])[cH:16][cH:17][c:18]21.[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:21][S:22]([O:23][CH:26]([CH2:27][O:24][S:25]([CH3:28])(=[O:29])=[O:30])[c:33]1[cH:34][cH:35][c:36]2[cH:37][n:38][n:39]([CH2:42][c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[c:40]2[cH:41]1)(=[O:31])=[O:32].[H-:2].[Na+:1]>>[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[N:10]1[C:11](=[O:20])[C:12]2([c:13]3[cH:14][c:15]([CH3:19])[cH:16][cH:17][c:18]31)[CH:26]([c:33]1[cH:34][cH:35][c:36]3[cH:37][n:38][n:39]([CH2:42][c:43]4[cH:44][cH:45][cH:46][cH:47][cH:48]4)[c:40]3[cH:41]1)[CH2:27]2

Participants

6

Reactant 5

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 166653HydrideHCID 581050281-Benzyl-5-methylindolin-2-oneHCID 76800943Methanesulfonic acid 2-(1-benzyl-1H-indazol-6-yl)-2-methanesulfonyloxy-ethyl ester

Product 1

HCID 772933811'-Benzyl-2-(1-benzylindazol-6-yl)-5'-methylspiro[cyclopropane-1,3'-indole]-2'-one

Sources & evidence

ORD record
ord-6aa212ae538b4eaab2cdf38664d73f69
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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