Trifluoroacetic acid → 1-[4-[5-[[2-Phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carbonyl]amino]-2-pyridinyl]benzoyl]pyrrolidine-2-carboxylic acid

HRID 2336615Notes

Reaction equation

HRID 2336615 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH:8]1[N:9]([C:13]([c:14]2[cH:15][cH:16][c:17](-[c:20]3[n:21][cH:22][c:23]([NH:26][C:27](=[O:28])[c:29]4[n:30][c:31](-[c:38]5[cH:39][cH:40][cH:41][cH:42][cH:43]5)[o:32][c:33]4[C:34]([F:35])([F:36])[F:37])[cH:24][cH:25]3)[cH:18][cH:19]2)=[O:44])[CH2:10][CH2:11][CH2:12]1.[OH:45][C:46]([C:47]([F:48])([F:49])[F:50])=[O:51]>>[O:5]=[C:6]([OH:7])[CH:8]1[N:9]([C:13]([c:14]2[cH:15][cH:16][c:17](-[c:20]3[n:21][cH:22][c:23]([NH:26][C:27](=[O:28])[c:29]4[n:30][c:31](-[c:38]5[cH:39][cH:40][cH:41][cH:42][cH:43]5)[o:32][c:33]4[C:34]([F:35])([F:36])[F:37])[cH:24][cH:25]3)[cH:18][cH:19]2)=[O:44])[CH2:10][CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 66738325Tert-butyl 1-[4-[5-[[2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carbonyl]amino]-2-pyridinyl]benzoyl]pyrrolidine-2-carboxylate

Product 1

HCID 667382171-[4-[5-[[2-Phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carbonyl]amino]-2-pyridinyl]benzoyl]pyrrolidine-2-carboxylic acid

Sources & evidence

ORD record
ord-34abbebb9e9842dcb295af2fdf81c363
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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