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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2336625Generated: October 26, 2026

Chloride → 3-chloro-N-[4-fluoro-2-hydroxy-5-(trifluoromethyl)phenyl]-isonicotinamide

https://huagongshe.com/reaction/2336625

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant3-Chloropyridine-4-carboxylic acidHCID 2735816—
Reactant2-Amino-5-fluoro-4-(trifluoromethyl)phenolHCID 53429149—
Product3-chloro-N-[4-fluoro-2-hydroxy-5-(trifluoromethyl)phenyl]-isonicotinamideHCID 66879586—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-47ecc0f2c0424f55a9339d61b5d6d0b5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)