Chloride → 3-chloro-N-[4-fluoro-2-hydroxy-5-(trifluoromethyl)phenyl]-isonicotinamide
Reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cl-:1].[Cl:2][c:3]1[c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][n:10][cH:11]1.[NH2:17][c:18]1[c:19]([OH:29])[cH:20][c:21]([F:28])[c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]1.[O:12]=[CH:13][N:14]([CH3:15])[CH3:16].[OH2:37]>>[Cl:2][c:3]1[c:4]([C:5](=[O:7])[NH:17][c:18]2[c:19]([OH:29])[cH:20][c:21]([F:28])[c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]2)[cH:8][cH:9][n:10][cH:11]1Participants
7
Sources & evidence
- ORD record
- ord-47ecc0f2c0424f55a9339d61b5d6d0b5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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