Sodium ion → 1-(3-Fluoro-5-(6-methoxynaphthalen-2-yl)pyridin-4-yl)ethanol

HRID 2336637Notes

Reaction equation

HRID 2336637 reaction equation
[Br:16][c:17]1[cH:18][n:19][cH:20][c:21]([F:26])[c:22]1[CH:23]([CH3:24])[OH:25].[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8]([B:13]([OH:14])[OH:15])[cH:9][c:10]2[cH:11][cH:12]1.[Na+:27].[Na+:28].[O-:29][C:30](=[O:31])[O-:32].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8](-[c:17]3[cH:18][n:19][cH:20][c:21]([F:26])[c:22]3[CH:23]([CH3:24])[OH:25])[cH:9][c:10]2[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 46416926-Methoxy-2-naphthaleneboronic acidHCID 699379091-(3-Bromo-5-Fluoro-pyridin-4-yl)-ethanol

Product 1

HCID 699373971-(3-Fluoro-5-(6-methoxynaphthalen-2-yl)pyridin-4-yl)ethanol

Sources & evidence

ORD record
ord-f376e756ab5346bf8869b0ea5f58bbee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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