1-Methylpiperazine → [5-(4-Methanesulfonyl-3-trifluoromethyl-phenyl)-4-methyl-thiazol-2-yl]-(4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-6'-yl)-amine

HRID 2337044Notes

Reaction equation

HRID 2337044 reaction equation
[CH3:29][N:30]1[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]1.[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([NH:8][c:9]2[s:10][c:11](-[c:15]3[cH:16][c:17]([C:25]([F:26])([F:27])[F:28])[c:18]([S:21](=[O:22])(=[O:23])[CH3:24])[cH:19][cH:20]3)[c:12]([CH3:14])[n:13]2)[n:7]1>>[c:2]1([N:33]2[CH2:32][CH2:31][N:30]([CH3:29])[CH2:35][CH2:34]2)[cH:3][n:4][cH:5][c:6]([NH:8][c:9]2[s:10][c:11](-[c:15]3[cH:16][c:17]([C:25]([F:26])([F:27])[F:28])[c:18]([S:21](=[O:22])(=[O:23])[CH3:24])[cH:19][cH:20]3)[c:12]([CH3:14])[n:13]2)[n:7]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 86761404(6-Chloro-pyrazin-2-yl)-[5-(4-methanesulfonyl-3-trifluoromethyl-phenyl)-4-methyl-thiazol-2-yl]-amine

Product 1

HCID 86761405[5-(4-Methanesulfonyl-3-trifluoromethyl-phenyl)-4-methyl-thiazol-2-yl]-(4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-6'-yl)-amine

Sources & evidence

ORD record
ord-15a35b59d7c2447084d48608c6e861ca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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