Sodium ion → Tert-butyl 4-((2-bromo-5-nitropyridin-4-yloxy)methyl)piperidine-1-carboxylate

HRID 2337446Notes

Reaction equation

HRID 2337446 reaction equation
[Br:23][c:24]1[n:25][cH:26][c:27]([N+:31](=[O:32])[O-:33])[c:28]([Cl:30])[cH:29]1.[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][OH:15])[CH2:12][CH2:13]1.[H-:16].[Na+:17].[O:18]=[CH:19][N:20]([CH3:21])[CH3:22]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][O:15][c:28]2[c:27]([N+:31](=[O:32])[O-:33])[cH:26][n:25][c:24]([Br:23])[cH:29]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 2764081Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylateHCID 596134182-Bromo-4-chloro-5-nitropyridine

Product 1

HCID 59613339Tert-butyl 4-((2-bromo-5-nitropyridin-4-yloxy)methyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-61f9c2c0d63d4b9dba0a4f8181fbd8ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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