Carbonate Ion → 2-Chloro-4-(3-hydroxy-2,3-dimethyl-5-oxopyrrolidin-1-yl)benzonitrile
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([Cl:10])[c:5]([C:6]#[N:7])[cH:8][cH:9]1.[C:62](=[O:63])([O-:64])[O-:65].[Cs+:66].[Cs+:67].[O:106]=[C:107]([CH:108]=[CH:109][c:110]1[cH:111][cH:112][cH:113][cH:114][cH:115]1)[CH:116]=[CH:117][c:118]1[cH:119][cH:120][cH:121][cH:122][cH:123]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[O:88]=[C:89]([CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1)[CH:98]=[CH:99][c:100]1[cH:101][cH:102][cH:103][cH:104][cH:105]1.[OH:11][C:12]1([CH3:19])[CH2:13][C:14](=[O:18])[NH:15][CH:16]1[CH3:17].[Pd:68].[Pd:69].[c:20]1([P:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:28]2[c:29]3[c:53]([cH:54][cH:55][cH:56]2)[C:50]([CH3:51])([CH3:52])[c:32]2[c:31]([c:36]([P:37]([c:38]4[cH:39][cH:40][cH:41][cH:42][cH:43]4)[c:44]4[cH:45][cH:46][cH:47][cH:48][cH:49]4)[cH:35][cH:34][cH:33]2)[O:30]3)[cH:57][cH:58][cH:59][cH:60][cH:61]1>>[c:2]1([N:15]2[C:14](=[O:18])[CH2:13][C:12]([OH:11])([CH3:19])[CH:16]2[CH3:17])[cH:3][c:4]([Cl:10])[c:5]([C:6]#[N:7])[cH:8][cH:9]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b9322c1a50be4acab68ed3d8fbde5a76
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…