Dichloromethane → Piperazine-1,4-dicarboxylic acid propyl ester tert-butyl ester

HRID 2337515Notes

Reaction equation

HRID 2337515 reaction equation
[CH2:21]([CH2:22][CH3:23])[O:24][C:25](=[O:26])[Cl:27].[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[Cl:28][CH2:29][Cl:30].[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([C:25]([O:24][CH2:21][CH2:22][CH3:23])=[O:26])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7998Propyl chloroformateHCID 8471TriethylamineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 66854950Piperazine-1,4-dicarboxylic acid propyl ester tert-butyl ester

Sources & evidence

ORD record
ord-71a25d2e7b184ebd93b3b3ff8fe76b5a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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