1,4-Dioxane → 3-[4-chloro-6-fluoro-3-hydroxy-2-(2-naphthoylamino)phenyl]-1-methyl-6-trifluoromethyl-2,4(1H, 3H)-pyrimidinedione
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][O:41][CH2:42]1.[NH2:1][c:2]1[c:3](-[n:11]2[c:12](=[O:23])[n:13]([CH3:22])[c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][c:16]2=[O:17])[c:4]([F:10])[cH:5][c:6]([Cl:9])[c:7]1[OH:8].[cH:24]1[c:25]([C:34](=[O:35])[Cl:36])[cH:26][cH:27][c:28]2[cH:29][cH:30][cH:31][cH:32][c:33]12>>[NH:1]([c:2]1[c:3](-[n:11]2[c:12](=[O:23])[n:13]([CH3:22])[c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][c:16]2=[O:17])[c:4]([F:10])[cH:5][c:6]([Cl:9])[c:7]1[OH:8])[C:34]([c:25]1[cH:24][c:33]2[c:28]([cH:27][cH:26]1)[cH:29][cH:30][cH:31][cH:32]2)=[O:35]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a2e6c6d0a2054a83bce60b1ceca3800b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…