Pyridine → Methyl 4-[[1-[methoxy(methyl)amino]-4-[(2-methylpropan-2-yl)oxy]-1,4-dioxobutan-2-yl]sulfamoyl]-3-phenylmethoxybenzoate

HRID 2337998Notes

Reaction equation

HRID 2337998 reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[O:27][C:28]([CH2:29][CH:30]([C:31](=[O:32])[N:33]([CH3:34])[O:35][CH3:36])[NH2:37])=[O:38].[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([O:14][CH2:15][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:7]([S:10](=[O:11])(=[O:12])[Cl:13])[cH:8][cH:9]1)=[O:22].[CH3:48][CH2:49][O:50][C:51](=[O:52])[CH3:53].[Cl:45][CH2:46][Cl:47].[cH:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1>>[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([O:14][CH2:15][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:7]([S:10](=[O:11])(=[O:12])[NH:37][CH:30]([CH2:29][C:28]([O:27][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:38])[C:31](=[O:32])[N:33]([CH3:34])[O:35][CH3:36])[cH:8][cH:9]1)=[O:22]

Participants

6

Reactant 5

HCID 1049PyridineHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 865881983-amino-N-methoxy-N-methyl-succinamic acid tert-butyl esterHCID 865882243-Benzyloxy-4-chlorosulfonyl-benzoic acid methyl ester

Product 1

HCID 87967171Methyl 4-[[1-[methoxy(methyl)amino]-4-[(2-methylpropan-2-yl)oxy]-1,4-dioxobutan-2-yl]sulfamoyl]-3-phenylmethoxybenzoate

Sources & evidence

ORD record
ord-93d32f7711574ec4bc7bb8e9518a5e3f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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