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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2338187Generated: November 2, 2026

2-(Bromomethyl)tetrahydro-2H-pyran → 1'-(4-fluoro-3-methoxybenzyl)-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

https://huagongshe.com/reaction/2338187

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)tetrahydro-2H-pyranHCID 141917—
Reactant4-(Chloromethyl)-1-fluoro-2-methoxybenzeneHCID 17964239—
ReactantSpiro[furo[2,3-g]-1,4-benzodioxin-8(7H),3'-[3H]indol]-2'(1'H)-one, 2,3-dihydroHCID 58224164—
Product1'-(4-fluoro-3-methoxybenzyl)-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-oneHCID 46194710—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-762edd173c2b459cabf569c48d75dd66
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)