Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 23382Generated: October 29, 2026

1-(4,5-dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-5-nitro-1H-indole → 1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-1H-indol-5-ylamine

https://huagongshe.com/reaction/23382

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4,5-dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-5-nitro-1H-indoleHCID 22574065—
SolventAcetonitrileHCID 6342—
Product1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-1H-indol-5-ylamineHCID 22574067—

Reaction Steps

1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-1H-indol-5-ylamine, (mp 215-217° C.) was prepared by reduction of the nitro group of compound 1-(4,5-dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-5-nitro-1H-indole, with TiCl3 in aqueous acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06852726B2
Source datasetuspto-grants-2005_02
ORD IDord-1c0f7b4c850c406c8254f9497e6ce443
Source noteuspto-grants-2005_02