Pyridine → Tert-butyl 2-[7-(methoxycarbonylamino)-9-oxofluoren-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

HRID 2338253Notes

Reaction equation

HRID 2338253 reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[Cl:37][C:38](=[O:39])[O:40][CH3:41].[NH2:1][c:2]1[cH:3][c:4]2[c:12]([cH:13][cH:14]1)-[c:11]1[c:6]([cH:7][c:8]([N:15]3[CH2:16][CH:17]4[CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH:21]4[CH2:22]3)[cH:9][cH:10]1)[C:5]2=[O:30].[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[NH:1]([c:2]1[cH:3][c:4]2[c:12]([cH:13][cH:14]1)-[c:11]1[c:6]([cH:7][c:8]([N:15]3[CH2:16][CH:17]4[CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH:21]4[CH2:22]3)[cH:9][cH:10]1)[C:5]2=[O:30])[C:38](=[O:39])[O:40][CH3:41]

Participants

5

Reactant 4

HCID 1049PyridineHCID 6586Methyl chloroformateHCID 8028TetrahydrofuranHCID 671636002-Amino-7-[N-Boc-3,7-diazabicyclo[3.3.0]octan-3-yl]-fluoren-9-one

Product 1

HCID 67163205Tert-butyl 2-[7-(methoxycarbonylamino)-9-oxofluoren-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

Sources & evidence

ORD record
ord-f3f23472610943e299c23bee4618fd31
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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