HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → 1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-7-methyl-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | Methanesulfonamide | HCID 72879 | — |
| Reactant | 1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-1H-indol-5-ylamine | HCID 22574067 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-7-methyl-1H-indole | HCID 22574045 | — |
Reaction Steps
N-1-(4,5-dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-1H-indol-5-yl]-methanesulfonamide, mp 232-233° C., was prepared from 1-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-1H-indol-5-ylamine by treatment with methane sulfonylchloride and pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06852726B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-9bba4ad2e62d451cbd558b074d46a657 |
| Source note | uspto-grants-2005_02 |