Bromide ion → tert-Butyl 1-(1-hydroxyprop-1-yl)-2-(tert-butyldimethylsilyloxy)-8-azaspiro[4.5]decane-8-carboxylate
Reaction equation
[Br-:28].[C:32](=[O:33])([OH:34])[O-:35].[CH2:29]([CH3:30])[Mg+:31].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH:1](=[O:2])[CH:3]1[CH:4]([O:20][Si:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:5][CH2:6][C:7]12[CH2:8][CH2:9][N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:11][CH2:12]2.[Na+:36]>>[CH:1]([OH:2])([CH:3]1[CH:4]([O:20][Si:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:5][CH2:6][C:7]12[CH2:8][CH2:9][N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:11][CH2:12]2)[CH2:29][CH3:30]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-0403cfe099414f94a41be0dd77fe1cb4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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