Ammonia → 3-[3-(2-{[5-chloro-4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyl-oxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Reaction equation
[CH3:81][OH:82].[CH:77]([OH:78])([CH3:79])[CH3:80].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][c:19]([C:20](=[O:21])[NH:22][c:23]4[c:24]([F:30])[cH:25][cH:26][cH:27][c:28]4[F:29])[cH:31][cH:32][cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1.[Cl:34][c:35]1[c:36]([N:44]2[CH2:45][CH2:46][CH:47]([N:50]3[CH2:51][CH2:52][N:53]([CH2:56][CH2:57][F:58])[CH2:54][CH2:55]3)[CH2:48][CH2:49]2)[cH:37][c:38]([O:42][CH3:43])[c:39]([NH2:40])[cH:41]1.[NH3:76].[c:59]1([CH3:60])[cH:61][cH:62][c:63]([S:64]([O-:65])(=[O:66])=[O:67])[cH:68][cH:69]1.[nH+:70]1[cH:71][cH:72][cH:73][cH:74][cH:75]1>>[c:2]1([NH:40][c:39]2[c:38]([O:42][CH3:43])[cH:37][c:36]([N:44]3[CH2:45][CH2:46][CH:47]([N:50]4[CH2:51][CH2:52][N:53]([CH2:56][CH2:57][F:58])[CH2:54][CH2:55]4)[CH2:48][CH2:49]3)[c:35]([Cl:34])[cH:41]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][c:19]([C:20](=[O:21])[NH:22][c:23]4[c:24]([F:30])[cH:25][cH:26][cH:27][c:28]4[F:29])[cH:31][cH:32][cH:33]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-4b7b5750e1ac4206b43682be83e6b190
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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