1,2-Dichloroethane → 1,4-Dioxaspiro[4.5]decane, 8-[4-(3,4-difluorophenyl)-3-cyclohexen-1-yl]-

HRID 2338619Notes

Reaction equation

HRID 2338619 reaction equation
[CH2:30]([Cl:31])[CH2:32][Cl:33].[F:1][c:2]1[cH:3][c:4]([C:9]2([OH:25])[CH2:10][CH2:11][CH:12]([CH:15]3[CH2:16][CH2:17][C:18]4([O:19][CH2:20][CH2:21][O:22]4)[CH2:23][CH2:24]3)[CH2:13][CH2:14]2)[cH:5][cH:6][c:7]1[F:8].[OH:26][CH2:27][CH2:28][OH:29]>>[F:1][c:2]1[cH:3][c:4]([C:9]2=[CH:10][CH2:11][CH:12]([CH:15]3[CH2:16][CH2:17][C:18]4([O:19][CH2:20][CH2:21][O:22]4)[CH2:23][CH2:24]3)[CH2:13][CH2:14]2)[cH:5][cH:6][c:7]1[F:8]

Participants

4

Reactant 3

HCID 111,2-DichloroethaneHCID 174Ethylene GlycolHCID 190011474-[4-Hydroxy-4-(3,4-difluorophenyl)cyclohexyl]cyclohexanone ethyleneacetal

Product 1

HCID 115590611,4-Dioxaspiro[4.5]decane, 8-[4-(3,4-difluorophenyl)-3-cyclohexen-1-yl]-

Sources & evidence

ORD record
ord-67e71cc37c0a43f9a919f65c0f06399a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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