Dimethyl Sulfoxide → 4-(6-Nitropyridin-3-yl)morpholine

HRID 2338791Notes

Reaction equation

HRID 2338791 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[n:6][cH:7]1.[C:17](=[O:18])([O-:19])[O-:20].[CH2:11]1[CH2:12][O:13][CH2:14][CH2:15][NH:16]1.[CH2:24]([N+:25]([CH2:26][CH2:27][CH2:28][CH3:29])([CH2:30][CH2:31][CH2:32][CH3:33])[CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH3:40].[CH3:41][S:42]([CH3:43])=[O:44].[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[I-:23].[K+:21].[K+:22]>>[c:2]1([N:16]2[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[n:6][cH:7]1

Participants

9

Reactant 8

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 8083MorpholineHCID 8857Ethyl AcetateHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 30165Iodide IonHCID 8176205-Bromo-2-nitropyridine

Product 1

HCID 29279734-(6-Nitropyridin-3-yl)morpholine

Sources & evidence

ORD record
ord-6bb0bf6be91c43d5b8cd17c3b49fc621
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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