Water → Tert-butyl 4-({1-[2-(4-cyanophenyl)ethyl]-4-hydroxypiperidin-4-ylmethyl}methylamino)benzoate
Reaction equation
[C:27](#[N:28])[c:29]1[cH:30][cH:31][c:32]([CH2:35][CH2:36][N:37]2[CH2:38][CH2:39][C:40]3([O:41][CH2:42]3)[CH2:43][CH2:44]2)[cH:33][cH:34]1.[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:12][NH:13][c:14]1[cH:15][cH:16][c:17]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:25][cH:26]1.[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1.[OH2:45]>>[CH3:12][N:13]([c:14]1[cH:15][cH:16][c:17]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:25][cH:26]1)[CH2:42][C:40]1([OH:41])[CH2:39][CH2:38][N:37]([CH2:36][CH2:35][c:32]2[cH:31][cH:30][c:29]([C:27]#[N:28])[cH:34][cH:33]2)[CH2:44][CH2:43]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-bc573c2137c449b0b9f0f282d9a26920
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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