Dichloromethane → (RS)-2-(2-Benzofuranylmethyl)-1-((5-(4-fluorophenyl)-2-methyl-thiazol-4-yl)-carbonyl)-piperidine

HRID 2338832Notes

Reaction equation

HRID 2338832 reaction equation
[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[Cl:40][CH2:41][Cl:42].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:14](=[O:15])[Cl:16])[n:10][c:11]([CH3:13])[s:12]2)[cH:6][cH:7]1.[o:17]1[c:18]([CH2:26][CH:27]2[NH:28][CH2:29][CH2:30][CH2:31][CH2:32]2)[cH:19][c:20]2[c:21]1[cH:22][cH:23][cH:24][cH:25]2>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:14](=[O:15])[N:28]3[CH:27]([CH2:26][c:18]4[o:17][c:21]5[c:20]([cH:19]4)[cH:25][cH:24][cH:23][cH:22]5)[CH2:32][CH2:31][CH2:30][CH2:29]3)[n:10][c:11]([CH3:13])[s:12]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 223241192-Methyl-5-(4-fluorophenyl)thiazole-4-carbonyl chlorideHCID 231462452-(2-benzofuranylmethyl)Piperidine

Product 1

HCID 10160068(RS)-2-(2-Benzofuranylmethyl)-1-((5-(4-fluorophenyl)-2-methyl-thiazol-4-yl)-carbonyl)-piperidine

Sources & evidence

ORD record
ord-81a67961bd504ea78be142ac68cda68e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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