Dimethylformamide → 2-(2-Tert-butoxycarbonyl-ethyl)-5-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzoic acid 2-trimethylsilanylethyl ester

HRID 2339262Notes

Reaction equation

HRID 2339262 reaction equation
[C:51](=[O:52])([O-:53])[O-:54].[CH3:1][Si:2]([CH2:3][CH2:4][O:5][C:6]([c:7]1[c:8]([CH2:14][CH2:15][C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[cH:9][cH:10][c:11]([OH:13])[cH:12]1)=[O:23])([CH3:24])[CH3:25].[CH3:26][c:27]1[c:28]([CH2:38][CH2:39][O:40][S:41]([c:42]2[cH:43][cH:44][c:45]([CH3:46])[cH:47][cH:48]2)(=[O:49])=[O:50])[n:29][c:30](-[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[o:31]1.[Cs+:55].[Cs+:56].[O:57]=[CH:58][N:59]([CH3:60])[CH3:61]>>[CH3:1][Si:2]([CH2:3][CH2:4][O:5][C:6]([c:7]1[c:8]([CH2:14][CH2:15][C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[cH:9][cH:10][c:11]([O:13][CH2:39][CH2:38][c:28]2[c:27]([CH3:26])[o:31][c:30](-[c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[n:29]2)[cH:12]1)=[O:23])([CH3:24])[CH3:25]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 120517392-(5-Methyl-2-phenyloxazol-4-yl)ethyl 4-methylbenzenesulfonateHCID 589791782-(2-Tert-butoxycarbonyl-ethyl)-5-hydroxy-benzoic acid 2-trimethylsilanyl-ethyl ester

Product 1

HCID 589792942-(2-Tert-butoxycarbonyl-ethyl)-5-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzoic acid 2-trimethylsilanylethyl ester

Sources & evidence

ORD record
ord-40f8e8599c3c4bfd929a90d5f18b3686
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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