Acetic Acid → Tert-butyl 2-(7-acetamido-9-oxofluoren-2-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

HRID 2339791Notes

Reaction equation

HRID 2339791 reaction equation
[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[CH3:31][C:32]([OH:33])=[O:34].[NH2:1][c:2]1[cH:3][c:4]2[c:12]([cH:13][cH:14]1)-[c:11]1[c:6]([cH:7][c:8]([N:15]3[CH2:16][CH:17]4[CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH:21]4[CH2:22]3)[cH:9][cH:10]1)[C:5]2=[O:30].[P-:35]([F:36])([F:37])([F:38])([F:39])([F:40])[F:41].[n:42]1([O:43][C:44]([N:45]([CH3:46])[CH3:47])=[N+:48]([CH3:49])[CH3:50])[c:51]2[n:52][cH:53][cH:54][cH:55][c:56]2[n:57][n:58]1>>[NH:1]([c:2]1[cH:3][c:4]2[c:12]([cH:13][cH:14]1)-[c:11]1[c:6]([cH:7][c:8]([N:15]3[CH2:16][CH:17]4[CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH:21]4[CH2:22]3)[cH:9][cH:10]1)[C:5]2=[O:30])[C:32]([CH3:31])=[O:33]

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 8028TetrahydrofuranHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 671636002-Amino-7-[N-Boc-3,7-diazabicyclo[3.3.0]octan-3-yl]-fluoren-9-one

Product 1

HCID 67163135Tert-butyl 2-(7-acetamido-9-oxofluoren-2-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

Sources & evidence

ORD record
ord-54de474983ab46d8aa45e51f83008677
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…