Trifluoroacetic acid → HCID 19964450, compound

HRID 233983Notes

Reaction equation

HRID 233983 reaction equation
[C:1]1([S:7]([N:10]([CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])[C:11]2[CH:12]=[C:13]([CH3:44])[C:14]3[N:18]=[C:17]([CH2:19][CH2:20][CH2:21][CH3:22])[N:16]([CH2:23][C:24]4[CH:29]=[CH:28][C:27]([C:30]5[C:31]([C:36]([O:38]C(C)(C)C)=[O:37])=[CH:32][CH:33]=[CH:34][CH:35]=5)=[CH:26][CH:25]=4)[C:15]=3[CH:43]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.FC(F)(F)C(O)=O>C(Cl)Cl>[C:1]1([S:7]([N:10]([CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])[C:11]2[CH:12]=[C:13]([CH3:44])[C:14]3[N:18]=[C:17]([CH2:19][CH2:20][CH2:21][CH3:22])[N:16]([CH2:23][C:24]4[CH:29]=[CH:28][C:27]([C:30]5[C:31]([C:36]([OH:38])=[O:37])=[CH:32][CH:33]=[CH:34][CH:35]=5)=[CH:26][CH:25]=4)[C:15]=3[CH:43]=2)(=[O:8])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 67708448HCID 67708448, compound

Product 1

HCID 19964450HCID 19964450, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 1 from tert.butyl 4'-[[6-(N-benzenesulphonyl-n-pentylamino)-2-n-butyl-4-methyl-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Sources & evidence

ORD record
ord-6f9f734121764d1982c22311ef9fde9b
Source dataset
uspto-grants-1997_01
Patent number
US05594003

Reaction notes

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