Trifluoroacetic acid → HCID 19964481, compound

HRID 233987Notes

Reaction equation

HRID 233987 reaction equation
[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([O:24]C(C)(C)C)=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:29]=[CH:30][C:31]([C:33]3[N:34]=[C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][N:36]4[CH:41]=3)=[CH:32][C:6]=2[N:5]=1)[CH2:2][CH3:3].FC(F)(F)C(O)=O>C(Cl)Cl>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([OH:24])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:29]=[CH:30][C:31]([C:33]3[N:34]=[C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][N:36]4[CH:41]=3)=[CH:32][C:6]=2[N:5]=1)[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 67708483HCID 67708483, compound

Product 1

HCID 19964481HCID 19964481, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 1 from tert.butyl 4'-[[2-n-propyl-5-(imidazo[1,2-a]pyridin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Sources & evidence

ORD record
ord-62356deec4164eefbcf4d652ee14333d
Source dataset
uspto-grants-1997_01
Patent number
US05594003

Reaction notes

Loading…