Trifluoroacetic acid → HCID 19964452, compound

HRID 233992Notes

Reaction equation

HRID 233992 reaction equation
[CH:1]1([C:5]2[N:9]([CH2:10][C:11]3[CH:16]=[CH:15][C:14]([C:17]4[C:18]([C:23]([O:25]C(C)(C)C)=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=4)=[CH:13][CH:12]=3)[C:8]3[CH:30]=[C:31]([C:35]4[N:39]([CH3:40])[C:38]5[CH:41]=[CH:42][CH:43]=[CH:44][C:37]=5[N:36]=4)[CH:32]=[C:33]([CH3:34])[C:7]=3[N:6]=2)[CH2:4][CH2:3][CH2:2]1.FC(F)(F)C(O)=O>C(Cl)Cl>[CH:1]1([C:5]2[N:9]([CH2:10][C:11]3[CH:12]=[CH:13][C:14]([C:17]4[C:18]([C:23]([OH:25])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=4)=[CH:15][CH:16]=3)[C:8]3[CH:30]=[C:31]([C:35]4[N:39]([CH3:40])[C:38]5[CH:41]=[CH:42][CH:43]=[CH:44][C:37]=5[N:36]=4)[CH:32]=[C:33]([CH3:34])[C:7]=3[N:6]=2)[CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 67708493HCID 67708493, compound

Product 1

HCID 19964452HCID 19964452, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 1 from tert.butyl 4'-[(2-cyclobutyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Sources & evidence

ORD record
ord-3a5b968d59a7494b8e98f808395a6427
Source dataset
uspto-grants-1997_01
Patent number
US05594003

Reaction notes

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