Dichloromethane → 2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide

HRID 2340232Notes

Reaction equation

HRID 2340232 reaction equation
[CH3:16][N:17]1[CH2:18][CH2:19][CH:20]([NH2:23])[CH2:21][CH2:22]1.[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:57][CH2:58][Cl:59].[F:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([O:14][CH3:15])[c:9]([N+:11](=[O:12])[O-:13])[cH:10]1.[P-:33]([F:34])([F:35])([F:36])([F:37])([F:38])[F:39].[n:40]1([O:41][C:42]([N:43]([CH3:44])[CH3:45])=[N+:46]([CH3:47])[CH3:48])[c:49]2[n:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[F:1][c:2]1[c:3]([C:4](=[O:6])[NH:23][CH:20]2[CH2:19][CH2:18][N:17]([CH3:16])[CH2:22][CH2:21]2)[cH:7][c:8]([O:14][CH3:15])[c:9]([N+:11](=[O:12])[O-:13])[cH:10]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 27375314-Amino-1-methylpiperidineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 579556142-Fluoro-5-methoxy-4-nitrobenzoic acid

Product 1

HCID 671177462-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide

Sources & evidence

ORD record
ord-e9fbb719893e4093ae10b1bac7eec53b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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