HCID 67708467, compound → HCID 19964683, compound

HRID 234035Notes

Reaction equation

HRID 234035 reaction equation
[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([O:24]C(C)(C)C)=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:29]=[C:30]([C:34]([NH:36][CH2:37][CH2:38][NH:39][CH3:40])=O)[CH:31]=[C:32]([CH3:33])[C:6]=2[N:5]=1)[CH2:2][CH3:3]>P(Cl)(Cl)(Cl)=O>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([OH:24])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:29]=[C:30]([C:34]3[N:39]([CH3:40])[CH2:38][CH2:37][N:36]=3)[CH:31]=[C:32]([CH3:33])[C:6]=2[N:5]=1)[CH2:2][CH3:3]

Participants

3

Reactant 1

HCID 67708467HCID 67708467, compound

Product 1

HCID 19964683HCID 19964683, compound

Reagents, catalysts & solvents 1

HCID 24813Phosphorus oxychlorideSolvent

Procedure

Prepared by heating of tert.butyl 4'-[[2-n-propyl-4-methyl-6-[2-(N-methylamino)-ethylaminocarbonyl]-1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate in phosphorus oxychloride and isolating analogously to Example 151.

Workup

  1. customPrepared
  2. customisolating analogously to Example 151

Sources & evidence

ORD record
ord-6a54b40e592246b8966143007f3ab63f
Source dataset
uspto-grants-1997_01
Patent number
US05594003

Reaction notes

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