Methanol → 5-{6-[2-(2-chloro-6-fluoro-phenyl)-ethylamino]-2-methoxy-pyrimidin-4-yl}-1H-pyridin-2-one
Reaction equation
[CH3:38][O-:39].[CH3:41][OH:42].[Cl:1][c:2]1[c:3]([CH2:9][CH2:10][NH:11][c:12]2[cH:13][c:14](-[c:20]3[cH:21][cH:22][c:23](=[O:26])[nH:24][cH:25]3)[n:15][c:16]([S:18][CH3:19])[n:17]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1.[Cl:27][c:28]1[cH:29][c:30]([C:31](=[O:32])[O:36][OH:37])[cH:33][cH:34][cH:35]1.[Cl:43][CH2:44][Cl:45].[Na+:40]>>[Cl:1][c:2]1[c:3]([CH2:9][CH2:10][NH:11][c:12]2[cH:13][c:14](-[c:20]3[cH:21][cH:22][c:23](=[O:26])[nH:24][cH:25]3)[n:15][c:16]([O:32][CH3:31])[n:17]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b823d8366ddf46d480b59de72e18064e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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