Tetrahydrofuran → (4-Bromo-1-trityl-1H-imidazol-2-yl)-(5-ethyl-2-fluoro-biphenyl-3-yl)-methanol
Reaction equation
[Br:21][c:22]1[n:23][c:24]([CH:46]=[O:47])[n:25]([C:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[cH:26]1.[CH2:1]([CH3:2])[c:3]1[cH:4][cH:5][c:6]([F:15])[c:7](-[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:8]1.[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:16][CH2:17][CH2:18][CH2:19][Li:20]>>[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH:46]([c:24]2[n:23][c:22]([Br:21])[cH:26][n:25]2[C:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[OH:47])[c:6]([F:15])[c:7](-[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:8]1Participants
5
Sources & evidence
- ORD record
- ord-6fd05312f3e14f73ba1132b5700736a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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