Dichloromethane → 2-[(4-Chloro-benzyl)-pyrrolidin-3-yl-amino]ethanol

HRID 2341182Notes

Reaction equation

HRID 2341182 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([N:13]([CH2:14][CH2:15][OH:16])[CH2:17][c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:32][CH2:33][Cl:34].[OH:25][C:26]([C:27]([F:28])([F:29])[F:30])=[O:31]>>[NH:8]1[CH2:9][CH:10]([N:13]([CH2:14][CH2:15][OH:16])[CH2:17][c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 667586553-[(4-Chloro-benzyl)-(2-hydroxy-ethyl)-amino]-pyrrolidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 231368872-[(4-Chloro-benzyl)-pyrrolidin-3-yl-amino]ethanol

Sources & evidence

ORD record
ord-8f1855bfecda451c90333d42c57bb073
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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