O-Xylene → Piroxicam

HRID 2341211Notes

Reaction equation

HRID 2341211 reaction equation
[NH2:21][c:22]1[n:23][cH:24][cH:25][cH:26][cH:27]1.[OH:1][C:2]1=[C:3]([C:15]([O:17][CH:16]([CH3:18])[CH3:19])=[O:20])[N:4]([CH3:14])[S:5](=[O:12])(=[O:13])[c:6]2[c:7]1[cH:8][cH:9][cH:10][cH:11]2.[c:28]1([CH3:29])[c:30]([CH3:31])[cH:32][cH:33][cH:34][cH:35]1>>[OH:1][C:2]1=[C:3]([C:15](=[O:17])[NH:21][c:22]2[n:23][cH:24][cH:25][cH:26][cH:27]2)[N:4]([CH3:14])[S:5](=[O:12])(=[O:13])[c:6]2[c:7]1[cH:8][cH:9][cH:10][cH:11]2

Participants

4

Reactant 3

HCID 7237O-XyleneHCID 104392-AminopyridineHCID 54686201Isopropyl-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide

Product 1

HCID 54676228Piroxicam

Sources & evidence

ORD record
ord-131565a8c291426b98cdf6ec9510dc57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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