Dichloromethane → 4-[7-(2-Methanesulfonyloxy-ethoxy)-quinazolin-4-yl]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:24][CH2:25][CH2:26][OH:27])[cH:21][cH:22][c:23]23)[CH2:12][CH2:13]1.[CH3:37][S:38]([Cl:39])(=[O:40])=[O:41].[CH:28]([N:29]([CH2:30][CH3:31])[CH:32]([CH3:33])[CH3:34])([CH3:35])[CH3:36].[Cl:42][CH2:43][Cl:44]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:24][CH2:25][CH2:26][O:27][S:38]([CH3:37])(=[O:40])=[O:41])[cH:21][cH:22][c:23]23)[CH2:12][CH2:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-c6b3963c721d4b1185feac4935db1148
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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