Bicarbonate Ion → 2-Amino-5-bromo-4-fluoro-3-hydroxy-6-methylbenzonitrile
Reaction equation
[B:15]([Br:16])([Br:17])[Br:18].[CH2:25]([Cl:26])[Cl:27].[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33].[NH2:1][c:2]1[c:3]([C:4]#[N:5])[c:6]([CH3:14])[c:7]([Br:13])[c:8]([F:12])[c:9]1[O:10][CH3:11].[Na+:20].[OH2:19].[OH:21][C:22](=[O:23])[O-:24]>>[NH2:1][c:2]1[c:3]([C:4]#[N:5])[c:6]([CH3:14])[c:7]([Br:13])[c:8]([F:12])[c:9]1[OH:10]Participants
8
Sources & evidence
- ORD record
- ord-17b8281c3f824605969ca5689aaf265a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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