Methyl iodide → Benzyl 3-[1-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]cyclopropyl]pyrrolidine-1-carboxylate

HRID 2342706Notes

Reaction equation

HRID 2342706 reaction equation
[Ag:29]=[O:30].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH:13]([C:16]2([NH:19][C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:17][CH2:18]2)[CH2:14][CH2:15]1.[CH3:27][I:28]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH:13]([C:16]2([N:19]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH3:27])[CH2:17][CH2:18]2)[CH2:14][CH2:15]1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 92152Silver(II) oxideHCID 221005141-Pyrrolidinecarboxylic acid, 3-[1-[[(1,1-dimethylethoxy)carbonyl]amino]cyclopropyl]-, phenylmethyl ester

Product 1

HCID 22100494Benzyl 3-[1-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]cyclopropyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-173d1e8ec4504984ad967073a817a53b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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