Bromide ion → 4-(2,2-dimethylpropyl)-2-{1-hydroxy-1-methyl-2-[4-(1-{[2-(trimethylsilyl)-ethoxy]methyl}-1,4,5,6-tetrahydro-7H-pyrazolo[3,4-b]pyridin-7-yl)phenyl]ethyl}-N,N-dimethyl-1H-imidazole-1-sulfonamide
Reaction equation
[Br-:1].[CH3:2][Mg+:3].[CH3:4][C:5]([CH2:6][c:7]1[n:8][c:9]([C:18]([CH2:19][c:20]2[cH:21][cH:22][c:23]([N:26]3[c:27]4[c:28]([cH:32][n:33][n:34]4[CH2:35][O:36][CH2:37][CH2:38][Si:39]([CH3:40])([CH3:41])[CH3:42])[CH2:29][CH2:30][CH2:31]3)[cH:24][cH:25]2)=[O:43])[n:10]([S:12](=[O:13])(=[O:14])[N:15]([CH3:16])[CH3:17])[cH:11]1)([CH3:44])[CH3:45].[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1>>[CH3:2][C:18]([c:9]1[n:8][c:7]([CH2:6][C:5]([CH3:4])([CH3:44])[CH3:45])[cH:11][n:10]1[S:12](=[O:13])(=[O:14])[N:15]([CH3:16])[CH3:17])([CH2:19][c:20]1[cH:21][cH:22][c:23]([N:26]2[c:27]3[c:28]([cH:32][n:33][n:34]3[CH2:35][O:36][CH2:37][CH2:38][Si:39]([CH3:40])([CH3:41])[CH3:42])[CH2:29][CH2:30][CH2:31]2)[cH:24][cH:25]1)[OH:43]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-9aaac71014b840e6b91e8419dae1fca8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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