Dimethylformamide → HCID 22998444, compound

HRID 234339Notes

Reaction equation

HRID 234339 reaction equation
CN(C=O)C.[S:6]([Cl:10])(Cl)(=[O:8])=[O:7].[CH2:11]([C:14]1[S:18][C:17]2[CH:19]=[CH:20][CH:21]=[CH:22][C:16]=2[CH:15]=1)[CH2:12][CH3:13]>>[CH2:11]([C:14]1[S:18][C:17]2[CH:19]=[CH:20][CH:21]=[CH:22][C:16]=2[C:15]=1[S:6]([Cl:10])(=[O:8])=[O:7])[CH2:12][CH3:13]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24648Sulfuryl chlorideHCID 590313HCID 590313, compound

Product 1

HCID 22998444HCID 22998444, compound

Procedure

2-Propylbenzo[b]thiophene-3-sulfonyl chloride was prepared by the method of Example 40B with DMF (3.6 mmoles, 0.28 ml), sulfuryl chloride (3.1 mmoles, 0.25 ml) and 2-propylbenzo[b]thiophene (1.8 mmoles, 0.32 g). Flash chromatography (3% ethyl acetate/hexanes) provided 0.28 g (56%) of a yellow solid.

Sources & evidence

ORD record
ord-a2f791748ab645768a2b0fc49c985049
Source dataset
uspto-grants-1997_01
Patent number
US05594021

Reaction notes

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