Hydrochloric Acid → tert-Butyl 3-(4-benzylpiperazin-1-yl)piperidine-1-carboxylate

HRID 2343448Notes

Reaction equation

HRID 2343448 reaction equation
[C:31](=[O:32])([OH:33])[O-:34].[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]([CH2:10][CH2:11][Cl:15])[CH2:13][CH2:14][Cl:12].[CH3:36][CH2:37][OH:38].[ClH:16].[ClH:1].[NH2:17][CH:18]1[CH2:19][N:20]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:21][CH2:22][CH2:23]1.[Na+:35]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]1[CH2:10][CH2:11][N:17]([CH:18]2[CH2:19][N:20]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:21][CH2:22][CH2:23]2)[CH2:14][CH2:13]1

Participants

7

Reactant 6

HCID 313Hydrochloric Acid2×HCID 702EthanolHCID 769Bicarbonate IonHCID 923Sodium ionHCID 5928N-BenzylnormechlorethamineHCID 5458091-BOC-3-Aminopiperidine

Product 1

HCID 86642500tert-Butyl 3-(4-benzylpiperazin-1-yl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-81193c32b5064fc0bec9ddc807e44325
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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