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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2343772Generated: November 2, 2026

Tetrahydrofuran → 1-(6-Chloropyridazin-3-yl)-1-(2,6-difluorophenyl)-4-(trimethylsilyl)but-3-yn-2-one

https://huagongshe.com/reaction/2343772

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantEthyl 3-(trimethylsilyl)propynoateHCID 568601—
ReactantNpc316347HCID 3280088—
Reactant3-Chloro-6-(2,6-difluorobenzyl)pyridazineHCID 57531239—
Product1-(6-Chloropyridazin-3-yl)-1-(2,6-difluorophenyl)-4-(trimethylsilyl)but-3-yn-2-oneHCID 57531229—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-77d503ec9c8243669549e633a69467e9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)