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Dimethylformamide → 2-Ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Sulfuryl chloride | HCID 24648 | — |
| 反応物 | 2-Ethyl-5-methylbenzo[b]thiophene | HCID 595344 | — |
| 生成物 | 2-Ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride | HCID 22998437 | — |
反応手順
2-ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride was prepared in the same manner as described in Example 40B. Reaction of DMF (6.5 mmoles, 0.50 ml), sulfurylchloride (5.5 mmoles, 0.44 ml) and 2-ethyl-5-methylbenzo[b]thiophene (3.2 mmoles, 0.57 g) yielded, after flash chromatography, using 2% ethyl acetate/hexanes, 0.58 g (66%) of an orange solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05594021 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-2e1a80b3724f4af0a24c693dc6673ddd |
| 出典メモ | uspto-grants-1997_01 |