Hydrochloric Acid → tert-Butyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate
Reaction equation
[BH4-:18].[CH3:26][CH2:27][OH:28].[ClH:20].[F:1][C:2]1([F:17])[CH2:3][N:4]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:5][CH2:6][C:7]1([OH:8])[OH:9].[Na+:19].[Na+:25].[O-:21][C:22]([OH:23])=[O:24]>>[F:1][C:2]1([F:17])[CH2:3][N:4]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:5][CH2:6][CH:7]1[OH:8]Participants
7
Sources & evidence
- ORD record
- ord-f58c937c644c44dfbbeea7592b53d107
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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