Bicarbonate Ion → Ethyl 2-[1-[2-[tert-butyl(dimethyl)silyl]oxy-2-(4-cyanophenyl)ethyl]piperidin-3-yl]acetate
Reaction equation
[Br:1][CH2:2][CH:3]([O:4][Si:5]([CH3:6])([CH3:7])[C:8]([CH3:9])([CH3:10])[CH3:11])[c:12]1[cH:13][cH:14][c:15]([C:16]#[N:17])[cH:18][cH:19]1.[C:20](=[O:21])([OH:22])[O-:23].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[NH:25]1[CH2:26][CH:27]([CH2:31][C:32](=[O:33])[O:34][CH2:35][CH3:36])[CH2:28][CH2:29][CH2:30]1.[Na+:24]>>[CH2:2]([CH:3]([O:4][Si:5]([CH3:6])([CH3:7])[C:8]([CH3:9])([CH3:10])[CH3:11])[c:12]1[cH:13][cH:14][c:15]([C:16]#[N:17])[cH:18][cH:19]1)[N:25]1[CH2:26][CH:27]([CH2:31][C:32](=[O:33])[O:34][CH2:35][CH3:36])[CH2:28][CH2:29][CH2:30]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7219918648b041ffb5fc53ab4b026eaa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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