Dimethyl Sulfoxide → N-(4-chlorophenethyl)-4-(2-cyclopropyl-4-formylphenoxy)benzamide

HRID 2344160Notes

Reaction equation

HRID 2344160 reaction equation
[CH3:38][S:39]([CH3:40])=[O:41].[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[CH:26]1([c:29]2[cH:30][c:31]([CH:32]=[O:33])[cH:34][cH:35][c:36]2[F:37])[CH2:27][CH2:28]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH2:7][NH:8][C:9]([c:10]2[cH:11][cH:12][c:13]([OH:16])[cH:14][cH:15]2)=[O:17])[cH:18][cH:19]1.[K+:20].[K+:21].[O-:22][C:23]([O-:24])=[O:25]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH2:7][NH:8][C:9]([c:10]2[cH:11][cH:12][c:13]([O:16][c:36]3[c:29]([CH:26]4[CH2:27][CH2:28]4)[cH:30][c:31]([CH:32]=[O:33])[cH:34][cH:35]3)[cH:14][cH:15]2)=[O:17])[cH:18][cH:19]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 574343473-Cyclopropyl-4-fluorobenzaldehydeHCID 60628097N-(4-chlorophenethyl)-4-hydroxybenzamide

Product 1

HCID 86643288N-(4-chlorophenethyl)-4-(2-cyclopropyl-4-formylphenoxy)benzamide

Sources & evidence

ORD record
ord-57aa94695c6a4048b21aac6010247c93
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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